IMWG consensus statement on the role of vertebral augmentation in multiple myeloma

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Following are the recommendations of the IMWG on role of minimally invasive percutaneous injection of polymethyl methacrylate (PMMA), first developed as “vertebroplasty” in France in the late 1980s, as treatment for painful vertebral compression fractures (VCFs). Consequences of VCF-related kyphosis Compression of abdominal contents Anorexia, weight loss Decreased lung capacity Limited exercise tolerance/physical activity Anterior loading of spine Subsequent fractures Increasing kyphosis and deformity Types of vertebral augmentation Vertebroplasty: fractured bone fragments are stabilized and strengthened by percutaneous injection of PMMA. Kyphoplasty:  inflation of a balloon in the vertebral body prior to PMMA injection can restore vertebral height and reduce kyphotic deformity in addition to stabilizing the fractured vertebral body. […]